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- 內容介紹
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Glucocorticosteriods (GCS) in Allergic Inflammation, An Issue of Immunology and Allergy Clinics
By David Skoner, MD
240 pages,
ISBN:1416026770
Contents
1. Molecular Mechanisms and Cellular Effects of GCS (Barnes) 2. Comparative Pharmacology, Bioavailability, Pharmacokinetics, and Pharmacodynamics of GCS (Derendorf) 3. Clonical Benefits in Asthma (including discussion of formulations and devices used for ICS delivery, and critical design elements of controlled clinical trials) (Bisgaard) 4. Clinical Benefits in Allergic Rhinitis/Sinusitis/Otitis Media (including discussion of formulation and devices used for INCS delivery, and critical design elements of controlled clinical trials) (van Cauwenberge) 5. Effects of GCS (oral CS/ICS/INCS and combinations of these) on the Eyes and Skin in Children and Adults (Bielory and Beltrani) 6. Effects of GCS (oral CS/ICS/INCS and combinations of these) on Bone Growth and Density in Children and Adults (Pederson) 7. Effects of GCS (oral CS/ICS/INCS and combinations of these) on the HPA Axis in Children and Adults (Eid) 8. Analysis of Benefit:Risk Ratio for Oral CS/ICS/INCS (and combinations of these) (Mortimer and Tattersfield) 9. Initiation (step-up/step-down), Dose Reductions, and Duration of GCS Therapy 10. GCS Respones: Varibility, Resistance, and Dose Relatedness for Benefits and Risk in Asthma and Allergic Rhintis (Spahn) 11. Steroid Phobia and Adherence-Problems, Solutions, Impact on Benefit/Risk Profile (Apter and Rao) 12. Evolution and Positoning of GCS in National/Interational Asthma and Allergic Rhinitis Guidelines (vs. other therapies) (Pauwels, Bousquet, van Cauwenberge, Brusselle and Joos)
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