Clinical Hematology - Textbook with CD-ROM
By Neal S. Young, MD, Stanton L. Gerson, MD and Katherine A. High, MD
1456 pages 550 ills
Trim size 8 1/2 X 10 7/8 in
Written by a young, innovative author group, this exciting new book gives you the clinically relevant aspects of hematology in an innovative, unique format. The book is structured to comprehensively cover the complete scope of hematology, but allows fast access to key information you need in everyday practice. A section on consultative hematology includes chapters on special populations (pregnancy, pediatrics, geriatrics), infections of marrow and blood, and hematologic problems of medical practice and surgery. You’ll also find a section on tools for the hematologist, covering clinical aspects of transfusion, transplantation, and the latest innovative laboratory procedures.
Provides critical information relevant to everyday practice, reflecting the way hematology is practiced today.
Covers basic science only as it relates to clinical practice.
Utilizes full-color photographs, illustrations, and functional drawings to highlight critical information and difficult concepts.
Uses consistent, templated chapters to make essential information uncommonly easy to find.
Offers a unique approach by innovative experts in the field.
Includes a CD-ROM containing all of the book’s figures, tables, algorithms, and charts all downloadable for PowerPoint® presentations, as well as a comprehensive reference library.
IBM - Single user Windows 2000, Windows ME, or Windows XP Pentium® II processor 233 MHz or higher 64 MB of available RAM 2 MB of available hard-disk space 8x or faster CD-ROM drive VGA monitor supporting 256 colors 800 x 600 screen resolution Acrobat Reader 28.8 or faster modem (optional for Internet access)
Macintosh OS X - Apple® PowerPC 166 MHz or higher Mac OS version 10.2 or higher 64 MB of available RAM 2 MB of available hard-disk space 8x or faster CD-ROM drive VGA monitor supporting 256 colors 800 x 600 screen resolution
Table of Contents
I. Basic Science of Hematology
* Hematopoiesis (including cytokines) * Globin/Heme * Erythrocyte structure * Red cell antigens * Granulocyte biology * Lymphocyte biology (including Ig) * Megakaryocytes and platelets * Coagulation factors * Vascular biology
II. Hematologic Diseases
Section 1. Diseases of Hematopoietic Cell Production
* Marrow failure * Acquired aplastic anemia * Fanconi anemia and dyskeratosis congenital * Pure red cell aplasia * Myelodysplastic syndromes * Hairy cell leukemia * Large granular lymphocytic leukemia * Mineral and vitamin deficiencies * Iron deficiency * Pernicious anemia and folate deficiency * Anemia of chronic disease
Section 2. Diseases of blood cell destruction
* Hemolytic anemias * Inherited HA * Sickle cell disease and other hemoglobinopathies * Thalassemias * Hereditary spherocytosis * RBC enzymopathies * Acquired HA * Autoimmune HA * Paroxysmal nocturnal hemoglobinuria * Mechanical HA * Immune thrombocytopenias * ITP, PTP, neonatal TP * Drug-induced thrombocytopenia * Heparin-induced thrombocytopenia * TTP and HUS * Neutropenias * Kostmann's and other onstitutional neutropenias * Agranulocytosis, pure white cell aplasia
Section 3. Malignant and proliferative hematologic diseases
* Leukemias * Leukemias: diagnosis and classifications * Acute myelogenous leukemia * Secondary MDS/AML * Chronic myelogenous and myelomonocytic leukemia * Acute lymphocytic leukemia * Pediatric leukemias * Chronic lymphocytic leukemia * Myeloproliferative diseases * Polycythemia vera and essential thrombocytosis * Myelofibrosis * Hypereosinophilia * Lymphomas and lymphoid malignancies * Biology of lymphoid malignancy * Hodgkins disease * Cutaneous lymphomas * CNS lymphomas * NonHodgkins lymphomas * Infectious malignancies * HIV-1 and HTLV-1-associated lymphomas * EBV, HHV-8 * Cryoglobulinemia * Multiple myeloma * MGUS * Macroglobulinemia * Histiocytosis * Amyloidosis * Mastocytosis * Diseases of the spleen
Section 4. Inherited and Acquired Metabolic Blood Diseases
* Porphyrias * Hemochromatosis * Familial Mediterranean fever * ALPS
Section 5. Diseases of Altered Coagulation Bleeding Disorders
* Platelet diseases * Inherited and acquired platelet disorders * von Willebrands disease * Coagulation factor disorders * Hemophilias (F VIII and IX deficiencies) * Acquired inhibitors * Thrombotic disorders * Inherited deficiencies of proteins C, S; factor V * Leiden * Anti-phospholipid syndrome * Heparin-induced thrombocytopenia
III. Consultative Hematology
Section 1. Hematology of Growth, Development, and Aging
* Hematologic complications of pregnancy * Hematology of the newborn * Pediatric hematology * Geriatric hematology
Section 2. Infections of Marrow and Blood Viruses
* Epstein-Barr virus * CMV * HHV-8 and other herpesviruses * Parvovirus B19 * HIV-1 and the hematology of AIDS * Hepatitis C * Dengue and hemorrhagic fever viruses * Protozoa * Malaria * Bartonellosis and others * Parasites * Hookworm
Section 3. Hematologic Problems of Medical Practice Anemia
* Hematologic drug reactions * Erythrocytosis * Kidney disease * Liver disease * Chronic bruising and the bleeding diathesis evaluation * Venous and arterial thrombosis * Anticoagulant therapy * Disseminated intravascular coagulation * Chemotherapy toxicities and complications
Section 4. Hematologic Complications in Surgery
* Evaluation of the acutely bleeding patient * Surgery in specific hematologic conditions
IV. Tools for the Hematologist
Section 1. Specialized practice
* HLA and Transplantation of Unrelated Cells * Marrow and blood transplantation * Supportive care during transplantation * Graft-versus-host disease * Transfusion medicine * Practice of blood component transfusion * Complications of transfusion (incl hepatitis, 2o iron overload)
Section 2. Laboratory methods
* Blood and marrow morphology (incl histochemistry) * Flow cytometry * Cytogenetics/FISH * DNA/functional genomics * Coagulation testing