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Immunologic Disorders in Infants and Children, 5th Edition
By E. Richard Stiehm, MD, Hans D. Ochs, MD and Jerry A. Winkelstein, MD
Approx. 1536 pages, Copyright 2004
Description
Written and edited by international experts in the field, this 5th Edition guides readers through all of the most recent advances in pediatric immunology—from development and function of the immune system…to the latest on primary and secondary immunodeficiencies…to the newest treatments and must-have advice on transplantation. Completely revised and expanded, the New Edition features two new editors, Dr. Hans Ochs and Dr. Jerry Winkelstein—plus 30 new authors—who join Dr. Stiehm in delivering up-to-the-minute information.
New to this Edition
Presents two new editors and 30 new authors.
Features 10 new chapters, including The Natural Innate Defense System, The Immunology of Pregnancy, Apoptosis Syndromes, Periodic Fever Syndromes and more. (See Table of Contents for a complete listing.)
Includes new material on the immunodeficiencies of immaturity and HIV infection—two fast-moving areas.
Provides expanded coverage of the secondary immunodeficiencies section, including a new chapter on genetic syndromes.
Includes extended discussions on immunodeficiency of malnutrition, splenic deficiency, surgical and anesthetic stress, and burns.
Presents greater coverage of combined and isolated cellular (T-cell) immunodeficiencies…all told, it discusses over 100 primary immunodeficiencies.
Places more emphasis on oncology in the hematology chapter.
Provides an updated review of bone marrow and solid organ transplantation.
Table of Contents
Part I: Development and Function of the Immune System
1. Ontogeny of Immunity 2. The T-Lymphocyte System 3. The B-Lymphocyte System: Fundamental Immunology 4. The B-Lymphocyte System: Clinical Immunology 5. The Polymorphonuclear Leukocyte System 6. The Mononuclear Phagocytic, Dendritic Cell and Natural Killer Cell Systems 7. The Serum Complement System 8. The Immune Response: Generation, Regulation and Maintenance 9. The Mucosal Defense System 10. The Natural (Innate) Defense System 11. The Immunology of Pregnancy
Part II: Primary Immunodeficiencies
12. Immunodeficiency Disorders—General Considerations 13. Antibody Deficiencies 14. Disorders of the IgA System 15. Combined Immunodeficiencies 16. Combined Immune Deficiencies Due to Purine Enzyme Defects 17. Other Well Defined Immunodeficiencies 18. Chromosomal Breakage Syndromes 19. Autoimmune Lymphoproliferative Syndrome (ALPS) 20. Phagocyte Disorders 21. Deficiencies of the Complement System
Part III: Secondary Immunodeficiencies
22. The Physiologic Immunodeficiency of Immaturity 23. Immune Responses to Malnutrition 24. Genetic Disorders Including Syndromic Immunodeficiencies 25. Immune Deficiency in Metabolic Diseases 26. Proliferative and Histiocytic Disorders 27. Immunosuppressive by Therapeutic Agents and Environmental Conditions 28. Immune Mechanisms in Infectious Disease 29. Pediatric Human Immunodeficiency Virus Infection 30. Stress-related Immunodeficiencies: Trauma, Surgery, Anesthesia, Burns, Exercise and Splenic Deficiencies
Part IV: Immunologic Aspects of Pediatric Illness
31. Allergic Diseases 32. Dermatologic Disorders 33. Pulmonary Disorders 34. Gastroenterologic and Liver Disorders 35. Rheumatic Disorders 36. Periodic Fever Syndromes 37. Autoimmune Endocrinopaties 38. Renal Disorders 39. Immune Mediated Hematologic and Oncologic Disorders 40. Immunologic Disorders of the Nervous System 41. Infection in the Compromised Host 42. Active and Passive Immunization in the Prevention of Infectious Diseases 43. Transplantation
Appendices
1. CD Designations 2. Cytokines and Chemokines
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