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Russell, Hugo & Ayliffe's Principles and Practice of Disinfection, Preservation and Sterilization
2004
Fourth Edition
Edited By: Adam P. Fraise, Hospital Infection Research Laboratory, City Hospital NHS Trust, Birmingham
Peter A. Lambert, Pharmaceutical Sciences Instiute, Aston University, Birmingham
Jean-Yves Maillard, School of Pharmacy and Biomolecular Sciences, University of Brighton, Brighton
Illustrations: 87
Pages: 688
Principles and Practice of Disinfection, Preservation and Sterilization is a highly respected, established text that has become a definitive reference in its field, covering in detail many methods of the elimination or prevention of microbial growth. The impact of micro-organisms and their threat to human health is a significant worldwide problem. Because of this constant war against micro-organisms, there is a need to understand the underlying mechanisms of microbial inactivation and resistance. Sterilization, disinfection and preservation are all designed to eliminate, present or frustrate the growth of micro-organisms in a wide variety of products.
This 4th edition is divided into two parts: principles and practice. Part I begins with an historical overview, followed by descriptions of the types of antimicrobial agents, factors affecting efficacy, evaluation, modes of action and types of resistance. Also included is a new chapter on the problems of biofilms, as there are particular difficulties in inactivating sessile bacteria.
Part II covers topics relating to sterilization and the control of these processes, including heat, radiation, gases and filtration. It also includes updated material on new and emerging technologies, discusses special problems in hospitals, dentistry and pharmaceutical practices, and concludes with a evaluation of the activity of agents and good manufacturing. The section relating to the spoilage of wood, paper, textiles, paints and stonework in the preservation section has been removed to ensure that this edition is focused on issues relating specifically to health and medicine.
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Contents
This 4th edition is divided into two parts: the first on principles and the second on practices.
Part I begins with an historical overview, followed by descriptions of the types of antimicrobial agents, factors affecting efficacy, evaluation, modes of action and types of resistance. Also included is a new chapter on the problems of biofilms, as there are particular difficulties in inactivating sessile bacteria.
Part II covers topics relating to sterilization and the control of these processes, including heat, radiation, gases and filtration. It also includes updated material on new and emerging technologies, discusses special problems in hospitals, dentistry and pharmaceutical practices, and concludes with an evaluation of the activity of agents and good manufacturing. The section relating to the spoilage of wood, paper, textiles, paints and stonework in the preservation section has been removed to ensure that this edition is focused on issues relating specifically to health and medicine.
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