Capillary Electrophoresis of Proteins and Peptides
Strege, Mark A. (Lilly Research Laboratories, Indianapolis, IN)
Lagu, Avinash L. (Lilly Research Laboratories, Indianapolis, IN)
Pub. Date: June 2004
Expert academic and pharmaceutical researchers describe their best capillary electrophoresis techniques for protein and peptide analysis. The authors present cutting-edge techniques for both capillary coatings and analytic detection via laser-induced fluorescence, for the development and commercialization of biopharmaceuticals, and for affinity capillary electrophoresis in the evaluation of protein binding, including the use of protein charge ladders. Areas of special interest covered include combining CE and capillary isoelectric focusing with electrospray mass spectrometry detection to perform proteomic studies and applications in the field of protein–ligand binding.