Blood and Bone Marrow Pathology
S N Wickramasinghe ScD, PhD, MB, BS, FRCP, FRCPath, FIBiol, Professor of Haematology, Imperial College School of Medicine, Director, Department of Haematology, St Mary's Hospital, London
ISBN 0443064369 · Hardback · 704 Pages · 1130 Illustrations
Churchill Livingstone · Published 2003
Detailed descriptions of the pathological features of blood and bone marrow in combination with over 1,000 high quality illustrations provide the reader with a single, comprehensive resource to assist in accurate diagnosis.
Histological and cytological appearances are correlated throughout to provide the reader with a complete and integrated approach to diagnostic interpretation and reporting.
An emphasis on differential diagnosis and diagnostic pitfalls provides the reader with a quick, practical solution to reporting difficult and problematic specimens.
Focus on the practical techniques of diagnostic laboratory testing reflects the realities of the pathologist's everyday work environment.
Consistent and logical organisational structure will enable the reader to locate essential information quickly and easily.
Section 1: Normal blood and bone marrow cells and hematopoiesis
Normal blood cells
Normal bone marrow cells: Development, cytology and ultrastructure
Normal bone marrow: histology, histochemistry and immunohistochemistry
Regulation of hematopoiesis
Section 2: Pathology of the marrow
Section 3: Disorders affecting erythroid cells
Investigation and classification of anaemia
Abnormalities of the red cell membrane
Inherited abnormalities of red cell enzymes
Abnormalities of the structure and synthesis of haemoglobin
Acquired haemolytic anaemias
Iron deficiency anaemia, anaemia of chronic disorder and iron overload
Congenital dyserythropoietic anaemias
Polycythaemia (the erythrocytoses)
Section 4: Disorders affecting leucocyte lineages
Abnormalities in leucocyte morphology and number
Disorders of phagocyte function
The chronic lymphoid and myeloid leukaemias and systemic mastocytosis
Abnormalities in immunoglobulin synthesising cells
Section 5: Abnormalities of hemostasis
Hemostatis: Principles of investigation
Disorders affecting megakaryocytes and platelets: inherited conditions
Acquired disorders affecting megakaryocytes and platelets
Inherited disorders of coagulation
Acquired bleeding disorders
Natural anticoagulants and thrombophilia
Section 6: Immunohematology
Blood groups on red cells, platelets and neutrophils
Transfusion medicine for the pathologist
Histocompatibility: HLA and other systems