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Osteoporosis in Men, 2nd Edition The Effects of Gender on Skeletal Health
-內分泌科
- 編號: 0-000000000123746023
- 作者:Eric S. Orwoll, John P. Bilezikian
- 原價-6400    - (熱賣價)5760      - 節省 ↓10%
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- 內容介紹
Osteoporosis in Men, 2nd Edition
The Effects of Gender on Skeletal Health
Edited by Eric S. Orwoll, John P. Bilezikian and Dirk Vanderschueren

Copyright 2010

Key Features

Brings together more eminent investigators and clinicians to interpret developments in this growing field.

Describes state-of-the-art research as well as practical approaches to diagnosis, prevention and therapy.


There is no book on the market that covers osteoporosis in men as comprehensively as this book.


Readership
Academic, medical, and pharmaceutical researchers in bone biology, endocrinology, and rheumatology; Medical researchers in pediatrics, internal medicine, orthopedics, primary care, geriatrics, obstetrics and gynecology, oncology, and nephrology.

Quotes

"The editors of Osteoporosis in Men, Second Edition have produced a comprehensive compendium about osteoporosis as it relates to men. An established group of experts has contributed to the second edition of this excellent book. The topics range from the basics of osteoporosis to sections on growth of the skeleton, aging, importance of nutrition, sex hormones, and the development of the disorder. Key sections of clinical relevance including diagnosis and treatment of osteoporosis in men are covered in depth. This book will serve as an excellent resource for established clinicians and investigators as well as for students and fellows."

--Richard Eastell, MD, FRCP, FRCPath, FMedSci, Professor of Bone Metabolism, Director of the NIHR Bone Biomedical Research Unit, Centre for Biomedical Research, Northern General Hospital, Sheffield, South Yorkshire, United Kingdom

"The 10 sections and total of 57 informative chapters in the second edition of the text Osteoporosis in Men constitute an impressive body of up-to-date information by leading experts on this important topic. The text is particularly useful because of its breadth extending from basic bone biology and environmental factors affecting skeletal development in men to clinical chapters on pathophysiology, diagnosis, and therapy. The editors have provided a comprehensive yet practical approach to the topic which makes the text useful to a broad potential audience ranging from trainees to established leaders in the field."

-- John T. Potts, Jr., MD, Director of Research and Physician-in-Chief emeritus, Massachusetts General Hospital, Jackson Distinguished Professor of Clinical Medicine, Harvard Medical School, Boston, MA, USA

"This thorough and comprehensive book integrates new, accessible, and informative material in the field. It will help investigators, as well as practitioners and students, to improve their understanding of male skeletal health and male skeletal loss. The additional knowledge, assembled in such a readable manner, should help us achieve one of our ultimate goals, namely better care of men with osteoporosis."


--Gerolamo Bianchi, MD, Department of Locomotor System, Division of Rheumatology, Azienda Sanitaria Genovese, Genova, Italy

Table of Contents

Section 1 - Essentials of bone biology



The Biochemistry of Bone: Composition and Organization

Adele L. Boskey


Bone Remodeling: Cellular Activities in Bone

David W. Dempster, Hua Zhou, Shi Shou Lu


Assessment of Bone Turnover Using Biochemical Markers

Patrick Garnero, Pawel Szulc


Fundamentals of Mineral Homeostasis

David A. Hanley, Shawn K. Davison


The Mechanical Properties of Bone

David P. Fyhrie


Assessment of Bone Architecture

Thomas F. Lang




Section 2 - Development and growth of the male skeleton



Skeletal Growth in Males

Qingju Wang, Ego Seeman


Pubertal Growth of the Male Skeleton

Vincent Gilsanz, Stefano Mora


The Effects of Sex Steroids on Bone Growth

Giampiero I. Baroncelli, Silvano Bertelloni


Nutritional Basis of Skeletal Growth

Connie M. Weaver, Elizabeth Haney


Physical Activity and Skeletal Growth

Heather M. Macdonald, Heather A. McKay, Melonie Burrows




Section 3 - Skeletal genetics



The Genetics of Peak Bone Mass

Luigi Gennari, Robert F. Klein, Serge Ferrari


Section 4 - Aging and the male skeleton



Age-Related Changes in Bone Remodeling and Micro Architecture

Roger Zebaze, Ego Seeman


Markers of Bone Remodeling and the Aging Skeleton

Serge Cremers, Christian Meier, Markus J. Seibel


Alterations in Mineral Metabolism in the Aging Male

Shonni J. Silverberg, Bismruta Misra


Change in Bone Size and Geometry with Aging

Pawel Szulc


Aging and Bone Density

Steven Boonen, Filip Callewaert, Katrien Venken, Dirk Vanderschueren


The Effect of Age on Material Properties

Charles H. Turner, Matt Allen, David Burr


Section 5, Nutritional issues



Calcium, Bone Strength and Fractures

Laura A.G. Armas, David P. Heaney, Joan M. Lappe


Vitamin D and Bone

Roger Bouillon, Christa Maes, Lieve Verlinden, Geert Carmeliet, Annemieke Verstuyf


Role of Dietary Protein in Bone Growth and Bone Loss

Rene Rizzoli




Section 6 - Sex steroids and the skeleton in men



The Molecular Biology of Sex Steroids in Bone: Similarities and Differences Among the Sexes

Stavroula Kousteni


Estrogen and the Skeleton - Rodents

Dirk Vanderschueren, Katrien Venken, Filip Callewaert, Steven Boonen


Estrogen and the Skeleton - Humans

Liesbeth Vandenput, Claes Ohlsson


Androgens and the Skeleton - Animal Models

Kristine Wiren, Eric Orwoll


Androgens and the Skeleton - Humans

Benjamin Z. Leder


Androgen Effects on the Skeletal Muscle

Shalender Bhasin, Rajan Singh, Ravi Jasuja, Thomas W. Storer

Section 7 - Fractures in men



Epidemiology of Fractures

Shreyasee Amin


Individualized Progress of Fractures in Men

Tuan V. Nguyen , John A. Eisman


Physical Activity, Physical Function and Fall and Fracture Risk in Older Men

Peggy Mannen Cawthon, Lynn Marshall


Economic Impact of Osteoporotic Fractures (vs women)

Terence O’Neill


Adverse Health Outcomes in Men with Osteoporosis

Deborah T. Gold, Stuart L. Silverman




Section 8. Metabolic bone disease in men



Idiopathic Osteoporosis

Jean-Marc Kaufman, Bruno Lepauw, Youri Taes, Stefan Goemeare


Glucocorticoid Induced Osteoporosis

Andrea Giustina, Gherardo Mazziotti


Testicular Dysfunction

David J. Handelsman, Christian Meier, Markus J. Seibel


Alcohol and Bone

Neil Binkley


Transplantation Osteoporosis

Elizabeth Shane, Juliet E. Compston, Emily Stein


Management of Fractures in Men with Impaired Renal Function

Paul D. Miller


Hyperparathyroidism

John P. Bilezikian, Claudio Marccoci


Hypercalciuria

Murray J. Favus


The Skeletal Phenotype of the Male Athlete

Clifford J. Rosen, Ann E. Maloney


Inherited and Related Disorders of Bone Matrix Synthesis in Men

Jay R. Shapiro




Section 9 - Diagnostic approach



Dual-Energy X-ray Absorptiometry (DXA) in Men

Neil C. Binkley, Robert A. Adler


Quantitative Ultrasound Diagnosis of Osteoporosis in Men

Robert A. Adler, Neil C. Binkley


Advanced Structural Assessment of Bone Using CT and MRI

X. Edward Guo, X. Sherry Liu, Felix W. Wehrli


Vertebral Fracture Assessments

Piet Geusens, Willem Lems


The Use of Bone Biopsies in the Diagnosis of Male Osteoporosis

Erik F. Eriksen, Johan Halse


Overall diagnostic strategy

Eric Orwoll


Section 10 - Therapy



Diagnostic Thresholds for Osteoporosis in Men

John A. Kanis, Anders Oden, Helena Johansson, Eugene V. McCloskey


Cost-Effectiveness of Interventions to Reduce Osteoporosis-Related Fractures in Men: Current Data, Controversies, and Challenges

John T. Schoesboe


Nutritional Therapy for Skeletal Health in Men

Deborah E. Sellmeyer, Diana M. Antoniucci


Exercise Programs for Patients with Osteoporosis

Dieter Felsenberg, Martin Runge


Calcitonin: History, Physiology, Pathophysiology and Therapeutic Applications

Sunil J. Wimalawansa


Treatment of Male Osteoporosis with Bisphosphonates

Socrates E. Papapoulos, Andrea Giusti


Treatment of Male Osteoporosis with Parathyroid Hormone

Monica Giotra, Felicia Cosman, John P. Bilezikian


Testosterone Therapy for Osteoporosis in Men

Kishore M. Lakshman, Andre B. Araujo, Shalendar Bhasin

57. Future Therapies: Strontium, SERMs, SARMs and New Therapies on the Horizon

Ghada El-Hajj Fuleihan, Mahmoud Tabbal



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